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CORINITE Tablet/ Syrup/ DS Suspension:

 
         
       
       
           
           
       
         
         
       
        Composition
         
        Each tablet of CORINITE contains:
        Phenylephrine hydrochloride IP : 5 mg Chlorpheniramine maleate: 2mg Paracetamol: 125mg Caffeine (anhydrous): 30mg
         
        Each 5 ml of CORINITE Syrup contains:
        Phenylephrine hydrochloride IP : 5 mg Chlorpheniramine maleate: 2mg Paracetamol: 125mg Sodium citrate: 60mg
         
        Each 5 ml of CORINITE DS Suspension contains:
        Phenylephrine hydrochloride IP : 5 mg Chlorpheniramine maleate: 2mg Paracetamol: 250mg Sodium citrate: 60mg
         
         
        Therapeutic Indications & Usage
         
        CORINITE is indicated for the temporary relief of cold symptoms, nasal congestion, runny nose, sore throat, sneezing, minor aches and pains, headaches and fever.
         
         
        Contraindications
         
        CORINITE is not advocated for those allergic to its ingredients. It is not to be given concomitant with theophylline, monoamine oxidase inhibitors (MAOIs), or for 2 weeks after stopping the MAOI, or in those with metabolic / respiratory alkalosis, hypocalcemia or hypochlorhydria. In view of its caffeine content, CORINITE is contraindicated during pregnancy.
         
         
        Precautions & Warnings
         
        CORINITE is to be advocated with caution in breathing problems (such as in chronic bronchitis), glaucoma, heart disease, high blood pressure, thyroid disease, diabetes, seizure disorder, anxiety or depression. Sedatives and tranquilizers will increase the drowsiness effect
         
        Safe use of CORINITE in pregnancy and lactation has not been established. CORINITE should not be preferably given for more than 5 days for pain, or 3 days for fever, unless prescribed. If sore throat persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea or vomiting medical consultation is to be sought. If nervousness, dizziness, or sleeplessness occurs, discontinue CORINITE.
         
        Antihistamines may impair mental and physical abilities, and hence caution is to be exercised in driving, or operating machinery whilst taking CORINITE.
         
        Sodium citrate (in CORINITE) is required to be advocated with caution in those with heart failure,renal impairment, edema, hypertension, eclampsia or aldosteronism.
         
        Abrupt stoppage of caffeine-containing products (CORINITE Tablet) is not advisable since it could cause withdrawal symptoms such as headache, anxiety, or muscle tension within 12 to 18 hours.
         
         
        Adverse Reactions
         
        The side effects on account of chlorpheniramine (in CORINITE) include drowsiness, xerostomia, excessive perspiration, skin rashes, cardiovascular and central nervous complaints, epigastric discomfort, anorexia, nausea, vomiting, diarrhea, constipation, thickened bronchial secretions, tightness of chest, wheezing and nasal stuffiness, and hematological changes.
         
        Side effects of paracetamol (in CORINITE) are rare, and usually mild. Skin rashes and other hypersen sitivity reactions could occur, and, on rare occasions, paracetamol could cause hematological changes.
         
        Caffeine (in CORINITE) could cause digestive side effects, restlessness, nervousness, tremor, headache, lightheadedness, dry skin, rash, and kidney dysfunction. Larger doses can lead aggravate ulcers, cause frequent urination, flushing, twitch, irritability, clotting abnormalities leading to hemorrhage and acidosis.
         
        Sodium citrate (in CORINITE) in large amounts can cause hypokalemia and metabolic alkalosis, especially if the renal function is impaired. Citrate salts can also have a laxative action. Drug Interaction
         
        CORINITE interacts with MAOIs; sedative and tranquillizers enhance its drowsiness potential. Beta blockers may potentiate the pressor effects and phenytoin interact with caffeine (in CORINITE).
         
         
        Recommended Dosage & Administration
         
        Adults
        CORINITE Tab: CORINITE Tab 4-6 hourly upto 4 times daily.
CORINITE Syp: 4-6 hourly upto 4 times daily
CORINITE DS suspension: 4-6 hourly upto 4 times daily.
         
        Children
        4-11 mths: ¼ CORINITE Syp 4-6 hourly upto 4 times daily
1-3 yrs: ¼-½ CORINITE Syp 4-6 hourly upto 4 times daily
4-8 yrs: ¾-1 CORINITE DS/Syp 4-6 hourly upto 4 times daily
8-12 yrs: 1-1½ CORINITE DS/Syp or ½-1 CORINITE Tab 4-6 hourly upto 4 times daily.
Or as prescribed.
         
         
        Presentations
         
        CORINITE Tablet: Blister strips of 10s.
CORINITE Syrup: Bottles of 60 ml
CORINITE DS Suspension: Bottles of 60 ml
         
       
         
       
       
         
       
 

 

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