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        Manav_Care_Duoflam N Tab
        Each 5 ml of DUOFLAM KID SUSPENSION contains:
        Paracetamol … 125 mg + Mefenamic Acid 50 mg
        Therapeutic Indications & Usage
        DUOFLAM KID SUSPENSION is indicated for pain and fever in children
        DUOFLAM KID SUSPENSION is not advocated for those allergic to its ingredients and in acute severe liver dysfunction. Intravenous (IV) paracetamol (DUOFLAM KID SUSPENSION Injection) is contraindicated in severe hepatocellular insufficiency and hepatic failure.
        Precautions & Warnings
        DUOFLAM KID SUSPENSION is to be advocated with caution in liver & kidney damage; it should also be given with caution in those with alcohol dependence. DUOFLAM KID SUSPENSION Injection especially must be advocated with caution in those with a creatinine clearance <30 ml/minute, chronic alcoholism, chronic malnutrition (low reserves of glutathione stores) and dehydration.
        In pregnancy and lactation DUOFLAM KID SUSPENSION should be given only if strictly required. DUOFLAM KID SUSPENSION should be coadministered with due precaution along with prokinetics such as metoclopramide, probenecid and cholestyramine.
        Mefenamic Acid (in Duoflam Kid Suspension) cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency.  Abrupt discontinuation of corticosteroids may lead to disease exacerbation.  Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids. The pharmacological activity of Mefenamic Acid (in Duoflam Kid Suspension) in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions
        Adverse Reactions
        Side effects of paracetamol (DUOFLAM KID SUSPENSION) are rare, and usually mild. Skin rashes and other hypersensitivity reactions could occur, and, on rare occasions, paracetamol could cause hematological changes. Pain at injection site can occur with DUOFLAM KID SUSPENSION IM / IV.
        Mefenamic Acid (Duoflam Kid suspension)Adverse Reactions Abdominal pain, dyspepsia, constipation, diarrhoea, nausea, GI ulcers; oedema; bronchospasm; headache, drowsiness, insomnia, visual disturbances; CHF, hypertension, tachycardia, syncope; urticaria, rash; thrombocytopenia, aplastic anaemia, agranulocytosis; tinnitus; elevated liver enzymes; abnormal renal function.
        Potentially Fatal: Autoimmune haemolytic anaemia; convulsions (overdosage).
        Drug Interaction
        Absorption of paracetamol from DUOFLAM KID SUSPENSION is increased by concomitant metoclopramide, and such other agents. Probenecid can decrease it's clearance whilst cholestyramine diminishes absorption of paracetamol (DUOFLAM KID SUSPENSION) when coadministered.
        Mefnamic Acid (in Duoflam Kid Suspension)Enhances activity of oral anticoagulants but rarely significant. Increases risk of GI irritation with alcohol. Increased ciclosporin, lithium toxicity and convulsions reported with ciprofloxacin. Absorption increased by magnesium hydroxide antacids. ACE inhibitor effects may be antagonised
        Recommended Dosage & Administration
        Oral administration
        As directed by physician.
        Duoflam Kid Suspension : Bottle pack of 60ml


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