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ARRESTIN:

 
         
       
       
           
           
       
         
         
       
        Composition
         
        Each tablet of ARRESTIN contains:
        Aceclofenac. . .100 mg
         
        Each sustained release tablet of ARRESTIN SR contains:
        Aceclofenac. . .200 mg
         
        Therapeutic Indications & Usage:
         
       

ARRESTIN is indicated for mild to moderate pain associated with inflammation. ARRESTIN SR is indicated for rheumatic disorders such as osteoarthritis, rheumatoid arthritis & ankylosing spondylitis, non-articular rheumatism, soft tissue injuries and various other   inflammatory disorders.

         
         
        Contraindications
         
        ARRESTIN / SR is contraindicated in patients with hypersensitivity to any of the ingredients, in those known to have bronchospasm or acute rhinitis or urticaria with aspirin or similar agents, presence of active or suspected peptic ulcer, gastrointestinal or other active bleeding, bleeding disorders, severe heart or kidney or liver failure. It is not advocated in small children below 18 months of age, & during the last trimester of pregnancy.
         
         
        Precautions
         
        ARRESTIN / SR should be administered with caution in patients with acid-peptic disease, inflammatory bowel disease, impaired renal or liver functions, blood dyscrasias, SLE, porphyria, hematopoietic and coagulation disorders, and in patients with hypersensitivity to aspirin or other NSAIDs.
         
         
        Warnings
         
        ARRESTIN / SR is to be advocated with due caution in those on diuretics, or otherwise at risk of hypovolemia. It should be used in pregnant women and nursing mothers only if absolutely required. Data on safety and efficacy of aceclofenac in children is not adequate. In those receiving longterm ARRESTIN / SR, periodical monitoring of renal and hepatic functions and blood counts is necessary
         
         
        Adverse Reactions
         
        The most common side effects are gastric pain, flatulence, nausea, vomiting, diarrhea & dyspepsia; rarely peptic ulcer and gastrointestinal bleeding occur. Infrequently, hypersensitivity reactions, skin reactions, taste perversion,malaise, change in appetite and weight, edema, palpitations, flushing, purpura and eye disorders are possible due to aceclofenac (ARRESTIN / SR). Neurological reactions possible include headache,drowsiness, insomnia, irritability and mood disturbances. ARRESTIN / SR can rarely cause hepatitis, renal dysfunction and blood dyscrasias on account of its aceclofenac content
         
         
        Drug Interactions:
         
        Aceclofenac (ARRESTIN / SR) could interact with oral thrombolytics, diuretics, cyclosporine, tacrolimus, phenytoin, digoxin, cimetidine, tolbutamide, phenylbutazone, amiodarone, miconazole, sulfaphenazole, methotrexate, lithium, and highly protein-bound drugs.
         
         
        Recommended Dosage & Administration
         
        ADULTS:
        1 ARRESTIN SR Tab od, or as prescribed
         
         
        Presentations:
         
        ARRESTIN Tablets:Blisters of 10s.
        ARRESTIN-SR Tablets: Blisters of 10s.
         
         
       
         
       
       
         
       
 

 

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