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P-FIXIM :

 
         
       
       
           
           
       
         
         
       
        Composition
         
        Each Film coated P-Fixim CV 200 tablet contains Cefpodoxime Proxetil equivalent to Cefpodoxime
200 mg and Clavulanic acid 125 mg.

Each 5 ml of P-Fixim 50 reconstituted suspension contains cefpodoxime 50 mg. Excipients q.s. Orange flavour
         
         
        Therapeutic Indications & Usage
         
        P-FIXIM indicated for the Acute Otitis Media,Community Acquired Pneumonia,Acute Exacerbation of Chronic Bronchitis,Pharyngitis,tonsillitis,acute maxillary sinusitis.
         
         
        Contraindications
         
        Cefpodoxime( in P-Fixim CV 200 , P-Fixim 50 )contraindicated to in patient with hypersensitivity with cephalosporin.
         
         
        Precautions & Warnings
         
        Before therapy with P-Fixim CV 200 is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cephalosporins, penicillins.
P-Fixim CV 200 is broad-spectrum antibiotics, should be prescribed with caution in individuals with a history of colitis. P-Fixim CV 200 should use pregnant women & nursing mother only if needed, because safety has not been clearly established.
         
         
        Adverse Reaction:
         
        Cefpodoxime( in P-Fixim CV 200 , P-Fixim 50 ) may cause side effects like diarrhea,nausea,vaginal infections,headache, abdominal pain,mild skin rashes,hives,chest pain,irregular heart beat.
         
         
        Drug Interactions
         
       

Carbamazepine: Elevated carbamazepine levels have been reported when cefpodoxime is administered concomitantly

         
        Warfarin and Anticoagulants: Increased prothrombin time, with or without clinical bleeding, has been reported when cefpodoxime is administered concomitantly.
         
        Oral Contraceptives: cefpodoxime may interfere with the effectiveness of birth control pills.
         
         
        Recommended Dosage & Administration
         
        Adults(Age 13 years & older)
Upper respiratory tract infections: 100mg bid for 5-10 days
Acute exacerbation of chronic bronchitis:200 mg bid for 14 days.
Acute community acquired pneumonia: 200mg bid for 14 days.
Uncomplicated gonorrhea :200mg single dose
Uncomplicated urinary tract infections: 100 mg bid for 7 days.
         
        Pediatric patients(age 2 months to 12 years)
Acute otitis media: 10mg/kg/day or 5 mg/kg for 12 hours for 5 days. Maximum daily dose is 400mg/day
Pharyngitis & tonsillitis: 10mg/kg/day or 5 mg/kg for 12 hours for 5-10 days. Maximum daily dose is 400mg/day
Acute maxillary sinusitis: 10mg/kg/day or 5 mg/kg for 12 hours for 10 days. Maximum daily dose is 400mg/day
         
         
        Presentation
         
        P-FIXIM CV 200-Blister of 10s
P-FIXIM 50- Bottle of 30ml
         
       
         
       
         
       
 

 

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