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SI-FIXIM-XL :

 
         
       
       
           
           
       
         
         
       
        Composition
         
        Each Film coated Si-fixim XL 100 tablet contain: Cefixime Trihydrate USP equivalent to Cefixime anhydrous 100mg, Dicloxacillin Sodium BP equivalent to Dicloxacillin ( as extended release) 500mg
         
        Each Film coated Si-fixim XL 200 tablet contain: Cefixime Trihydrate USP equivalent to Cefixime anhydrous 200mg, Dicloxacillin Sodium BP equivalent to Dicloxacillin (as extended release) 500mg
         
         
        Therapeutic Indications & Usage
         
        In Respiratory tract infections such pneumonia,bronchitis & Soft skin tissue infections.
         
         
        Contraindications
         
        SI-FIXIM-XL 100/200 is not advocated for those with a history of hypersensitivity to beta-lactams, e.g. penicillins and cephalosporins.
         
         
        Precautions & Warnings
         
        SI-FIXIM-XL should be advocated with caution in presence of renal impairment or GI disease,particularly colitis. Periodic assessment of hematopoietic function is advisable during prolonged SI-FIXIM-XL therapy. SI-FIXIM-XL is not ideally meant for pregnant lady or lactating mother; however, it could be only if strictly necessary. Nursing discontinuation temporarily must be considered whilst taking SI-FIXIM. Safety and efficacy of cefixime (SI-FIXIM) in children less than 6 months old have not been established.
         
         
        Adverse Reactions
         
        The most frequent adverse effect is gastrointestinal (GI) complaints, and diarrhea incidence is 16%. Other side effects include hypersensitivity reactions, liver / renal dysfunction, headaches, dizziness, seizures,hematopoietic changes, genital pruritus, vaginitis, candidiasis.
         
         
        Recommended Dosage & Administration
         
        In Severe infections or nonresponders: 1 SI-FIXIM-Xl 200Tab bid.
In SWITCH THERAPY: 1 SI-FIXIM-Xl 200Tab bid
In hepatic disease no change in dose,but in severe renal impairment half the recommended dose.
         
         
        Presentation
         
        SI-FIXIM-XL 100/200: Blister strips of 10s
         
       
         
       
         
       
 

 

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