Home / Products / Formulations / Svizera Healthcare / Inspira / SI-FIXIM



        Each dispersible tablet of SI-FIXIM 50 / 100 DT contains:
Cefixime trihydrate Equivalent to anhydrous cefixime … 50 / 100 mg
Each tablet of SI-FIXIM 200 DT contains: Cefixime trihydrate Equivalent to anhydrous cefixime … 200 mg Each 5 ml of reconstituted SI-FIXIM Dry Syrup contains: Cefixime trihydrate Equivalent to anhydrous cefixime … 50 mg
        Therapeutic Indications & Usage
        SI-FIXIM is indicated for the treatment of infections caused by susceptible bacteria:
• Upper respiratory tract infections, such as pharyngitis, sinusitis, otitis media, tonsillitis.
• Lower respiratory tract infections, such as acute bronchitis and acute exacerbation of chronic bronchitis.
• Uncomplicated urinary tract infections.
• Uncomplicated gonorrhea.
        SI-FIXIM is not advocated for those with a history of hypersensitivity to beta-lactams, e.g. penicillins and cephalosporins.
        Precautions & Warnings
        SI-FIXIM should be advocated with caution in presence of renal impairment or GI disease, particularly colitis. Prolonged use of SI-FIXIM could result in overgrowth of non-susceptible organisms. If superinfections occur (usually involving Aerobacter, Pseudomonas or Candida spp), SI-FIXIM should be discontinued and/or appropriate therapy instituted.
Periodic assessment of hematopoietic function is advisable during prolonged SI-FIXIM therapy. SI-FIXIM is not ideally meant for pregnant lady or lactating mother; however, it could be only if strictly necessary. Nursing discontinuation temporarily must be considered whilst taking SI-FIXIM. Safety and efficacy of cefixime (SI-FIXIM) in children less than 6 months old have not been established.
SI-FIXIM must be coadministered with carbamazepine, warfarin and other anticoagulants.
        Adverse Reactions
        The most frequent adverse effect is gastrointestinal (GI) complaints, and diarrhea incidence is 16%. Other side effects include hypersensitivity reactions, liver / renal dysfunction, headaches, dizziness, seizures, hematopoietic changes, genital pruritus, vaginitis, candidiasis.
        Drug Interaction
        Elevated carbamazepine levels occur when cefixime (SI-FIXIM) is coadministered. When given with warfarin / anticoagulants, the prothrombin time is elevated. Probenecid can decrease it's clearance, whilst cholestyramine diminishes absorption of paracetamol (in NIMCET Plus) when coadministered.
        Recommended Dosage & Administration
Susceptible infections: 1 SI-FIXIM 200 Tab / 2 SI-FIXIM 100 DT bid, or 2 SI-FIXIM Tabs od, or as prescribed.
        Uncomplicated cervical / urethral gonococcal infections: 2 SI-FIXIM Tabs , or as prescribed.
<50 kg: 8 mg/kg/day of SI-FIXIM Suspension / SI-FIXIM 50 / 100 DT either as single dose or in two divided doses. >50 kg:

SI-FIXIM 50 / 100 DT: Blister strips of 10s.


SI-FIXIM 200 DT: Blister strips of 10s.

        SI-FIXIM Dry Syrup: Bottles of 30 ml.


"Maneesh" Pharmaceuticals   |  Manufacturing Excellence  |   International Presence  |  Products
"Maneesh" for Doctors  |  Our Team  |  For the Patients  
Contact Us  |  Feedback  |  Site Map  | Search Maneesh